Thoughts: Systems Biology, Feedback, and Metaphorical Universality

To understand biological life’s (<as far as we presently know> carbon based metabolism) emergent properties, one must understand how all the parts of a biological system/s are functionally integrated. Systems biology and reductionism compliment each other in this investigation.


Basics of Systems Strategy Theory

1st-inventory as many parts as possible (e.g. known proteins in a cell)

2nd-investigate how each part behaves in relation to others working in the system (e.g. protein to protein interactions)

3rd-pool all data from many research terms/teams and apply them into System Network Models (tech. sense).


Feedback Regulation

Feedback: mechanism enabling biological processes to self-regulate.

Feedback Regulation: the output / the product of a process that regulates that very process

Negative Feedback: most common form of regulation. The accumulation of an end product of a process slows that very process.

Positive Feedback: an end product speeds up its production (e.g. blood clotting after an injury <chemicals released by platelets which attract more platelets.>)

Bit of Last night’s dream

it rained so I remember little except

aguing with one and a half paragraphs of printed on Paper text

Photocopy

not original

Hardy’s A Mathematician’s Apology

not arguing with Hardy but the text bit as living thing

there were other people there that I could not see

felt stuffy and full of egos (academia?)

I’m annoyed to be there and can’t remember how or why I am there.

A Mathematician’s Apology finishes presenting itself.

it’s brilliant and funny. feels too true to be true. Straw man.

it’s ‘feedback from the galley’ time

despite wild applause, NO ONE has anything to say

this pisses me off

so I talk, challenge, blah blah.

the subject matter is not my specialty

the other dummies prob know more than me, but don’t have anything to say?

the one and half paragraph seems relieved someone is talking

we have a good discussion

I Slept Like A Champ Yesterday.

I woke up and thanked you.

“The rhythms fell slow,” one of us said.

The other one of us immediately noted the line was not being spoke in the original sense.

Bespoke all over again

I laugh at this to give myself another opportunity to smile up at you.


I had to handle errands.

marginalia: see how easy errand goes errant

but there was nothing to doubt, dear.

I narrated to you.

(I narrate for you)

Even when time’s changes and the earth’s rotations

make it impossible to know where or when you are.

even when you are not there or here,

when you could not know you were there….

unless…but who could be that magical really?


Still,

I know you are

glad

I am.

(any reading thereof)

I hope your feet are warm.


It rained.

It stopped.

It remains grey.

The mountains are obscured by clouds.

You coulda gone weeks without knowing they were there at all

I suspect

back when our opposable thumbs were still novels


Hey there’s an attractive Japanese couple to my right.

waiting for the light to cross on foot

made me wish I was on foot

they are young compared to us

they laugh and smile and gesture wildly.

Now I’m smiling.

They pretend to be sign twirlers for some surreptitious business or affair,

spinning the invisible boards. dropping it, kicking it back up and catching it on their backs

It’s good panto. I can see it. The invisible they indicate.

I dream they are trying to indicate you to me.

Watch “Jeff Buckley- Lover, You Should’ve Come Over” on YouTube

This is the partner song of Mojo Pin for me.

And I think there’s an accordian playing!

Watch “Jeff Buckley – Mojo Pin” on YouTube

it’s raining, I just woke up

heard this in the absence of the person I miss

Paying homage / don’t own rights

Dream memory

2 hours worth of dreams about words (like a tetris dream)

Lots of waterways (like a means to get around)

I was told I could land a plane should I choose

It was a big plane

I feel like I’m supposed to

back to sheep for now

Remember it-it Rhymes

(Claude) Levi-Strauss did not invent denim, but rather anthropological stucturalism.

P.S. my audience is myself here. feel free to disapprove

Fin de Siècle & Lebensraum (words on index cards you are trying to discern)

Fin de Siècle is French for “end of century.”

Reference the English idiom “turn of the century” (turn of the screw?)

Re: the closing of one era and the onset of another

Term refers to the end of the 19th century – period of ‘degeneration’ but simultaneously a period of hope for a new beginning.

Spirit of fin de siècle: refers to cultural hallmarks that were recognized as prominent in the 1880’s and 1890s

i.e. ennui, cynicism, pessimism.

Artists catalyzed this as impetus for movements like Symbolism and Modernism


Also, a general belief that civilization leads to decadence (see Freud. Civilization and Its Discontents).

Also, became a major influence on fascism. (?)

Watch “Neil Young – Dead Man Theme (long version)” on YouTube

electric comes in like thunder rolling

It’s Not A Stretch

Tendons turn before hips.

Calves cramp before pointes.

Ligaments lech over muscles.

Impeccable imbecile.

Lovely Repetition.

That is the first secret.

you tell me the second

(and third);

and, I’ll tell you if I already knew that

already

HARTZ. American Exceptionalism (pt2).

— Picking up)

Americans enjoyed bourgeois liberty. “Not the aristocratic freedom of their motherland, but a middle-class and democratic freedom.” (Tocqueville).

The U.S. had learned to combine liberty and democracy as the French had not. They did not suffer what Tocqueville called a “democratic revolution.” They (in the U.S.) all belonged to a middle class. There was no prolonged struggle to bring down aristocracy.

Tocqueville said:

The Americans had this great advantage, that they attained democracy without sufferings of democratic revolution and that they were born equal instead of becoming so.


Hartz expands Tocqueville’s analysis in two directions:

1. Employed the French aristocratic insights to explain the striking absence of an American socalist or militant working-class tradition.

America’s white immigrants could pursue middle-class goals freely, because social homogeneity kept most Americans from thinking systematically about class difference. American political culture lacked the European categories necessary to the expression of antagonism.

Whereas a European socialist might see class confrontation, most Americans saw only a pluralist conflict among narrowly defined interests, and they behaved accordingly, by shunning class-based policies. Hartz argued the failure of the bourgeoisie to develop class-consciousness left American workers ideologically crippled.

A triumphant middle-class can take itself for granted. (Tocqueville).

2. Applied Tocqueville’s arguement to American political ideas that were thoroughly liberal.

Hartz argued that they began with Locke and, “stay with [him] by virtue of an absolute and irrational attachment” that made America as uniquely “indifferent to the challenge of socialism” as it had earlier been “unfamiliar with the heritage of feudalism.”

Because there was no feudalism to attack, American liberals, unlike their European counterparts (or Locke), could reject entirely the idea of a powerful government. They didn’t need it to use as a weapon against an older order. In conjunction with insensitivity to class differences, this fear of governmental power has consistently weakened movements for large-scale welfare programs, economic regulation, or socialism.

Because American industrial development generally resembled Europe’s, Hartz cast his Exceptionalism thesis in strongly political and cultural terms. What has differentiated politics in the U.S., are limits that have been imposed on economically induced political change by the agreement of liberal beliefs and programs.

Watch “Nile Rodgers on Bowie, Madonna and Chic’s first new album in more than 25 years” on YouTube

How do you deny what you have smelled for days?

Watch “Nile Rodgers on Bowie, Madonna and Chic’s first new album in more than 25 years” on YouTube

Super fun.

Hey Gents: How do you shut up a guitarist? Ask ’em to play from sheet music!

How do you shut up a pianist? Take away the sheet music!

Favorite quote: bring me the disco king!

Harmony not unison.

Steve Winwood (sp?) Back in the High Life, anyone?

Here’s to the long breakdowns; let’s take the Good Times and try to hop on it..

Hey,

Oh, 1982 Bowie: quite! Very interesting indeed.

Dream Recall from past few

speaking French and English simultaneously. I don’t speak French

KB and CB and RB from Tavern with JKennedy (ha) from Venture Crew

shift in management.

I assume its KB that’s gonna get the boot.

he’s phoned it in the entire time I’ve worked with him

he looks stoned and like he knows whats coming and could not give an eff.

Martin works bar.

I’ve got the 90’s and 80’s (11 table section-should be split b/w 2 Servers

man, I am garbage

outta practice

a 4 top goes down

then a 3 top.

I’m weeded!

after 2 tables! garbage

I consider walking out.

I don’t

Vitamin C(an) D(o)

My sister once (and repeatedly since!) insists Vitamin C by Can sums up the grey months in Seattle. She’s not wrong. Ok, fine. She’s right.

That’s hard to say as an older sister.

She also told me about this

Sadness Hides the Sun thing.

Too sad, sister.

Party foul!


Party fowl.

I’m chicken o’ that kinda sad.

Cut it out.

Now

Pitter Patter

There’s blue sky

and the sun’s jutting outta the grey

but it’s not gonna last all day!

Sometimes you gotta run at it

or walk at quickly

(seriously girl-don’t blow them knees out!)

ha

Watch “A Tribe Called Quest – Can I Kick It” on YouTube

Paying homage (double homage!)

Can l kick it?

yes you can!

doesn’t matter if you’re minor or major

Watch “First In Flight” on YouTube

Thank you Blackalicious. These guys are poets and musicians. Rare combo. Chills.

Zagreus (oft confused with a dude up a tree)

Camus’ Zagreus once “laughed and added, ‘You see Mersault, all the misery and cruelty of our civilization can be measured by this one stupid axiom: happy nations have no history,’ ” incorporating time and nations into the excruciatingly existential search for ‘metaphysical truth.’

Watch “Paul Simon ~ “Diamonds on the Soles of Her Shoes”” on YouTube

Classic in my family’s house.

We are from LA originally.

This album taught me what a National Guitar is.